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女性绝经后血清雌激素水平与颈动脉粥样硬化的关系 被引量：28

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摘要 目的探讨女性绝经后血清雌激素水平与颈动脉粥样硬化的关系。方法选择绝经后女性127例,经颈部血管超声检查,测量颈总动脉中膜厚度(intimal-medial thicknessI,MT),按颈总动脉平均IMT分成3组。内膜正常组:13例I,MT<1.0 mm;内膜增厚组:43例,1.0 mm≤IMT<1.2 mm;斑块形成组:71例I,MT≥1.2mm。检测血清雌激素、血脂等指标。结果与正常组比较,内膜增厚组中Apo-B和高血压患病率均增高(P<0.05),CHO、TG、LDL-C明显增高,E2明显降低(P<0.01);斑块形成组CHO、TG、LDL-C及高血压患病率均明显增高,E2明显降低(P<0.01)。logistic回归分析显示IMT与CHO、TG、LDL-C及高血压呈正相关,而与E2水平呈负相关。结论女性绝经后雌激素水平下降是导致血脂代谢紊乱、颈动脉粥样硬化的危险因素。
作者 李志超 宁显忠 胥向红 王红艳
机构地区 辽宁医学院 辽宁医学院附属第三医院神经科
出处 《广东医学》 CAS CSCD 北大核心 2010年第23期3110-3111,共2页 Guangdong Medical Journal
关键词 绝经女性 雌激素 颈动脉粥样硬化
分类号 R543.4 [医药卫生—心血管疾病]
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参考文献7

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二级参考文献9

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共引文献30

同被引文献255

引证文献28

二级引证文献179

广东医学
2010年 第23期

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