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2型糖尿病患者肾小球滤过率测定及影响因素分析

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摘要 T2DM患者79例,根据UAER分为A组,n=30(UAER<20ug/min)、B组,n=27(UAER20~200ug/min)、C组,n=22(UAER>200ug/min),所有患者进行放射性核素肾动态显像测定GFR,并测定UAER、ACR、血肌酐(Scr)、血尿素氮(BUN)、糖化血红蛋白(HbA1c)和收缩压(SBP)。结果随着UAER的增加,GFR逐渐下降(P<0.01),ACR逐渐升高(P<0.05),GFR与UAER、ACR呈显著负相关(P<0.01);C组的HbA1c、SBP、Scr、BUN较A组及B组显著升高(P<0.05)。结论 GFR是反映糖尿病肾病早期发病的敏感指标,结合UAER、ACR能更准确更全面反映糖尿病肾病的病变程度,为早期糖尿病肾病的防治提供依据。
出处 《实用糖尿病杂志》 2010年第6期42-43,共2页 Journal of Practical Diabetology
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参考文献7

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