摘要
目的 探讨围生期和出生后巨细胞病毒（CMV）感染对婴儿生长发育及神经心理发育的影响.方法 对48例围生期和生后CMV感染及22例非CMV感染的婴儿进行随访观察,对比两组出生、3月龄及1岁龄时体格发育变化,并分别对两组1岁龄婴儿进行发育商（DQ）测试.结果 出生及3月龄时两组婴儿的身长、体质量、头围比较差异无显著性（P〉0.05）,1岁龄时身长、体质量、头围均值均在正常范围,感染组与非感染组比较差异均无显著性（P〉0.05）.两组1岁龄时大运动、精细运动、适应性、语言、社交能力DQ比较差异均无显著性（P〉0.05）,总DQ均值在正常范围,两组亦无显著性差异（P〉0.05）.两组DQ值按评价等级划分,大都处于正常级别范围,差异亦无显著性（χ2=1.026,P〉0.05）.结论 围生期和出生后CMV感染对婴儿近期的生长发育及神经心理发育没有明显的不良影响.
Objective To study the effects of perinatal and postnatal cytomegalovirus（CMV） infection on infantile physical development and nerves mental growth. Methods We observed forty-eight cases of perinatal and postnatal CMV infection infants and twenty-two cases of non-CMV infected infants. We compared the physical development between two groups at birth ,3 months and 1 year of age, and evaluated development quotient （DQ） at 1 year of age. Results There were no significant differences of baby length,weight, head circumference between two groups at birth and 3 months （P 〉 0.05）. The averages of baby length,weight,and head circumference were all in the normal range,which showed no significant differences between two groups（P 〉 0. 05）. There were no significant differences in DQ of rough movement,accurate movement, adaptability, language and sociality ability between two groups at 1 year of age （P 〉 0.05）. The averages of total DQ were in the normal range, which showed no significant difference between two groups as well （P 〉 0. 05）. According to the evaluation hierarchies, DQ values of two groups were mostly in normal level range, and there also was no significant difference（x2 = 1. 026, P 〉 0. 05）. Conclusion The perinatal and postnatal cytomegalovirus（CMV） infection has no significant adverse effects on infantile physical development and neuro-psychological development.
出处
《中国小儿急救医学》
CAS
2010年第6期508-510,共3页
Chinese Pediatric Emergency Medicine
关键词
巨细胞病毒
围产期和出生后感染
生长发育
发育商
Cytomegalovirus
Perinatal and postnatal cytomegalovirus infection
Physical development
Development quotient
