摘要
目的了解医院产碳青霉烯酶肺炎克雷伯菌感染及耐药情况。方法对2008-2009年住院患者的细菌培养结果及药物敏感试验结果进行检索,对产碳青霉烯酶肺炎克雷伯菌感染的阳性病例进行调查分析。结果产碳青霉烯酶肺炎克雷伯菌感染患者住院时间较长,平均43.8 d,患者病情均较重,呼吸道感染为主占50.00%,碳青霉烯药物使用时间平均为7.9 d,敏感抗菌药物只有妥布霉素和阿米卡星,阿米卡星的敏感率为100.00%,妥布霉素的敏感率为95.24%,中敏率为4.76%。结论合理使用抗菌药物,尽可能按照药敏试验结果选用敏感的抗菌药物,做好多药耐药菌消毒隔离制度的落实与督查,做好手卫生,是控制产碳青霉烯酶肺炎克雷伯菌感染的有效措施。
OBJECTIVE To study the information of nosocomial infection and drug resistance of Klebsiella pneumoniae carbapenemase.METHODS A retrospective survey of the results of bacterial culture and drug sensitivity and the cases of K.pneumoniae infection was undertaken in the period from 2008 to 2009.RESULTS The patients of infection K.pneumonuiae Carbapenemase（KPC） had a longer stay which was 43.8 days in average and all patients had the more serious conditions.The respiratory tract infection accounted for 50.00% and the average time of using carbapenemase drugs was 7.9 days.The sensitive antibiotics were tobramycin with sensitive rate of 95.24% and amikacin with sensitive rate of 100.00%.The average of sensitive rate was 4.76%.CONCLUSION The key measures to prevent infection of K.pneumoniae carbapenemase（KPC） are using antibiotics drugs reasonablely,choosing antibiotics according to the drug sensitivity test and implementing the supervising system of drug resistance disinfection and isolation and hand hygiene.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2011年第3期563-565,共3页
Chinese Journal of Nosocomiology
基金
黑龙江省卫生厅课题(2010-018)
