摘要
目的 分析山东省地方性氟中毒的病情现状,为制订防治策略提供科学依据.方法 2008年按照国家〈2007年地方病防治项目技术实施方案〉的要求,选择山东省19个县（市、区）以村为单位进行流行病学调查,氟离子选择电极法测定水氟和8～12岁儿童尿氟,Dean法诊断儿童氟斑牙,临床和X线摄片检查16岁以上成人氟骨症.结果 在19个县（市、区）中,共调查了186个村,水氟均值≤1.00 mg/L的村44个,占23.66%（44/186）;＞1.00 mg/L的村142个,占76.34%（142/186）;水氟最大值为8.88 mg/L.8～12岁儿童氟斑牙总检出率为66.35%（4518/6809）,氟斑牙指数为1.55,缺损率为15.39%（1048/6809）.儿童尿氟＞1.40mg/L的人数占83.29%（2149/2580）,最高值为31.92 mg/L.16岁以上成人氟骨症临床和X线检出率分别为6.37%（5577/87 607）、20.23%（229/1132）.结论 山东省地方性氟中毒病情仍然比较严重,防治形势依然比较严峻,须进一步加大防治力度.
Objective To investigate the current status of endemic fluorosis in Shandong province, and to provide scientific evidence for the development of control strategies. Methods According to ＂The National Technical Scheme for Endemic Disease Control in 2007＂, 19 counties were chosen to carry out the epidemiological investigation in 2008. Water and urinary fluoride were determined by F-ion selective electrode, dental fluorosis of children aged 8 to 12 were diagnosed by Dean method and skeletal fluorosis of adults over the age of 16 were examined clinically and by X-rays. Results In 19 counties, 186 villages were surveyed, 44 villages were found with mean water fluoride ≤ 1.00 mg/L, accounting for 23.66%（44/186）;the value 〉 1.00 mg/L in 142 villages,accounting for 76.34% （142/186）;maximum water fluoride 8.88 mg/L. Total detection rate of dental fluorosis of children aged 8 to 12 was 66.35% （4518/6809）, dental fluorosis index was 1.55, and defect rate was 15.39%（1048/6809）. Children with urinary fluoride 〉 1.40 mg/L was 83.29%（2149/2580）, and the maximum value was 31.92 mg/L. Detection rates of skeletal fluorosis clinically and by X ray among adults over 16 years were 6.37%（5577/87 607） and 20.23% （229/1132）, respectively. Conclusions Endemic fluorosis in Shandong province is still serious, prevention efforts need to be further increased.
出处
《中国地方病学杂志》
CAS
CSCD
北大核心
2011年第1期51-55,共5页
Chinese Jouranl of Endemiology
基金
中央补助地方公共卫生专项资金地方病防治项目（2007）
关键词
地方病
氟中毒
牙
氟骨症
数据收集
Endemic diseases
Fluorosis, dental
Osteofluorosis
Data collection
