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视神经脊髓炎与水通道蛋白4抗体及其检测方法的研究进展 被引量:2

Relation of neuromyelitis optica with aquaporin-4 antibody and its detection method: an update
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摘要 视神经脊髓炎(neuromyelitis optica,NMO)是一种严重的、突发性的中枢神经系统炎性脱髓鞘性的自身免疫性疾病,主要累及视神经和脊髓[1].1884年Eugène Devic报道1例45岁法国妇女呈亚急性发病的视力障碍和双下肢瘫痪、尿潴留,后经尸检证实为累及视神经和胸腰段脊髓的严重脱髓鞘和坏死,称之为NMO[2].随着NMO病例报道的增多以及相关研究的进展,人们发现NMO和部分多发性硬化(multiple sclerosis,MS)的临床表现相似.
作者 李世容 楚兰
出处 《中华神经医学杂志》 CAS CSCD 北大核心 2011年第1期97-99,共3页 Chinese Journal of Neuromedicine
关键词 视神经脊髓炎 水通道蛋白4抗体 Neuromyelitis Optica Aquaporin-4 antibody
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参考文献26

  • 1Wingerchuk DM,Lennon VA,Lucchinetti CF,et al.The spectrum of neuromyelitis optica[J].Lancet Neurol,2007,6(9):805-815.
  • 2吴卫平.关注视神经脊髓炎的特殊性[J].中华神经科杂志,2009,42(6):361-364. 被引量:10
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二级参考文献31

  • 1李海峰,丛志强.合并多发性硬化或视神经炎的重症肌无力临床分析[J].中华神经科杂志,2005,38(4):261-264. 被引量:6
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共引文献28

同被引文献31

  • 1Lennon VA, Wingerchuk DM, Kryzer T J, et al. A serum antibody marker of neuromyelitis optica: distinction from multiple sclerosis [J]. Lancet, 2004, 364(9451): 2106-2112.
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  • 10Lennon VA, Kryzer T J, Pittock S J, et al. lgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel[J]. J Exp Med, 2005, 202(4): 473-477.

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