摘要
目的:探讨头颈部浆细胞肉芽肿(PCG)的临床诊断及治疗方法。方法:回顾性分析3例头颈部PCG患者的临床资料。1例行鼻内镜手术完全切除,术后使用鼻用和口服类固醇激素;2例行上颌窦根治术部分切除肿物,术后结合口服类固醇激素药物和局部放疗,其中1例并行化疗。结果:治疗后1例患者随访5年,鼻腔未见肿物复发,上颌窦开口处及窦腔内黏膜光滑无分泌物;1例患者术后2年行鼻窦CT检查,残留肿物未见增生;1例患者3年后行鼻窦CT检查,肿物较术前减小,患者无明显张口受限,疗效满意。结论:头颈部PCG较为少见,虽然是一种炎性反应性病变,但临床体征及影像学表现类似于恶性肿瘤。该病变具有侵袭性,治疗首选手术切除,不能完全切除者应结合激素和放、化疗,预后较好。
Objective：To discuss the diagnosis and treatment of plasma cell granuloma in the head and neck region.Method：Retrospective analysis of 3 cases of plasma cell granuloma occured in head and neck.One case treated with endoscopic surgery and nasal and oral steroids after operation.Two cases treated with Caldwell-Luc style resection,followed by oral steroids and radiotherapy,one of the two cases combined with chemotherapy simultaneously.Result：The patient done with endoscopic surgery followed up for 5 years,there was no tumor recurrence in the nasal cavity and maxillary sinus openings and sinus lining.Paranasal sinus CT was examed on the patient done with partial resection and radiotherapy 2 years after operation,no residual tumor proliferation.The third patient underwent paranasal sinus CT examination 3 years after operation,and no limitation of mouth opening was found.Conclusion：The incidence rate of Plasma cell granuloma occured in head and neck is low.It is an inflammatory disease,but its physical signs and imaging findings are similar to malignant tumors.Because of the invasion feature,surgical resection should be the first choice,and if combined with radiotherapy and chemotherapy,the prognosis could be better.
出处
《临床耳鼻咽喉头颈外科杂志》
CAS
CSCD
北大核心
2011年第3期103-104,108,共3页
Journal of Clinical Otorhinolaryngology Head And Neck Surgery
关键词
头颈部肿瘤
浆细胞肉芽肿
外科手术
head and neck neoplasms
plasma cell granuloma
surgical procedures
operative
