沙利度胺治疗尿毒症相关皮肤瘙痒的疗效观察被引量：10

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摘要目的探讨沙利度胺治疗尿毒症相关皮肤瘙痒的有效性以及安全性。方法从我院血液透析中心抽取有瘙痒主诉的患者64例,随机分成2组。2组患者均予相同剂量规律透析,治疗组患者予沙利度胺200 mg,qd;对照组患者予安慰剂对照,治疗4,8,12周分别评价疗效。结果治疗后瘙痒评分,治疗组为(7.3±1.9)分,对照组为(14.2±2.5)分(P<0.001)。治疗组有效率为70.5%,对照组有效率为23.5%,2组比较P=,0.004.治疗8周、12周有效率达到82.3%.结论沙利度胺减少皮肤炎症因子的释放,能有效减轻尿毒症患者的瘙痒症状,改善患者的生活质量。

作者曾贵林

机构地区江门市新会区人民医院

出处《基层医学论坛》 2011年第1期36-37,共2页 The Medical Forum

关键词沙利度胺尿毒症维持性血液透析皮肤瘙痒

分类号 R692.5 [医药卫生—泌尿科学]

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