摘要
芽孢杆菌葡萄糖脱氢酶在辅酶再生方面具有良好的应用前景,因而受到了广泛关注。本文结合葡萄糖脱氢酶的三维结构和生理生化特性,尝试建立起其结构与功能方面的相关关系,为葡萄脱氢酶的体外改造提供有价值的信息,并指出了目前应用上存在的问题,对发展趋势做了展望。
Glucose dehydrogenases from Bacillus sp.are competitive candidates in the NAD（P）H regeneration and thus have attracted wide attention.This review is an attempt to elaborate the correlation between the structure and function of the enzyme based on the three-dimensional structure of glucose dehydrogenase and it＇s physiological and biochemical properties,and thus provide valuable information for the in vitro engineering of glucose dehydrogenase.In addition,problems that exist in current application of this enzyme are pionted out and the development trend in this area is previewed.
出处
《科技通报》
北大核心
2011年第1期50-56,共7页
Bulletin of Science and Technology
基金
"863"计划(2007AA06Z329)
关键词
葡萄糖脱氢酶
芽孢杆菌
结构
功能
glucose dehydrogenase
Bacillus sp.
structure
function
