摘要
目的:探讨孟鲁司特钠对于治疗小儿咳嗽变异性哮喘的疗效。方法:对照组所有患儿采用常规治疗方法,研究组在对照组的相关治疗方法基础上,加入孟鲁司特钠治疗,根据患儿年龄段不同控制用药量,对患儿的临床症状缓解情况、咳嗽消失时间、6个月后复发情况、治疗前后血尿常规、肝肾功能等进行记录与分析。结果:研究组患儿的治疗有效率达到96.67%,显著优于对照组的83.33%;两组患儿经过治疗后均得到了不同程度的临床症状缓解,研究组患儿临床症状的缓解时间与咳嗽消失时间较对照组都有显著的缩短;研究组的复发率也明显少于对照组患儿。结论:孟鲁司特钠对治疗小儿咳嗽变异性哮喘具有显著的治疗效果。作为口服药剂,使患儿于每晚服用孟鲁司特钠不仅会产生较好的治疗效果,且患儿依从性较高,大大减少了激素类药物的用量,避免了激素过量易造成患儿全身副作用的隐患,适合于临床推广使用。
Objective：To disouss the effect of montelukast sodium for the treatment of children with cough variant asthma. Methods：The patients in control group were all treated with conventional treatment. The ones in study group were treated by montelukast sodium on the basis of treatment in control group, and eontrolod the dosage according to the different age. To record and analysis the relief of clinical symptoms, cough disappeared time, recurrence after 6 months,routine urine before and after treatment, liver and kidney function and so on. Results：The treatment efficiency of study group （96.67%）was significantly better than the control group （83.33%）. The patients in two groups obtained varying degrees of clinical symptoms after treatment. The time of cough disappear and clinical remission in study group ,was significantly shorter than control group, and the rate of relapse in study group was less than control group significantly. Conclusion：The treatment of montelukast sodium for children with cough variant asthma has significant therapeutic effect, and it could reduce the amount of hormone drugs.
出处
《医学信息（中旬刊）》
2011年第2期369-370,共2页
Medical Information Operations Sciences Fascicule
