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脑脊液腺苷脱氨酶测定在小儿结核性脑膜炎诊断中的应用 被引量:4

Determination of adenosine deaminase in cerebrospinal fluid in children with tuberculous meningitis diagnosis
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摘要 目的:探讨脑脊液腺昔脱氨酶(ADA)活性测定在小儿结核性脑膜炎诊断中的应用价值。方法:选择结核性脑膜炎35例、病毒性脑膜炎36例、化脓性脑膜炎32例及非脑膜炎40例,测定并比较各组患者脑脊液ADA活性及阳性率。结果:结核组脑脊液ADA活性和阳性率明显高于非结核组,差异有显著性(P<0.05);结核性脑膜炎组治疗前后脑脊液ADA活性比较,差异有显著性(P<0.05)。结论:脑脊液腺苷脱氨酶可作为诊断结核性脑膜炎的重要参考指标。 Objective:To investigate the cerebrospinal fluid adenosine deaminase (ADA) activity was measured in the diagnosis of tuberculous meningitis in chil- dren in the application. Methods :35 cases of tubercular meningitis, viral meningitis,36 cases,32 cases of purulent meningitis and 40 cases of non -meningitis were determined and compared ADA activity in cerebrospinal fluid of patients in each group and the positive rate. Resuits:TB and positive cerebrospinal fluid ADA activity was significantly higher than that of non -tuberculosis group, the difference was significant (P 〈 0.0) ;tuberculous meningitis eerebrospinal fluid ADA activity before and after treatment, the difference was significant ( P 〈 0.05 ). Conclusion: Cerebrospinal fluid adenosine deaminase in diagnosis of tuberculous meningitis as an important reference index.
出处 《医学信息(中旬刊)》 2011年第2期373-374,共2页 Medical Information Operations Sciences Fascicule
关键词 腺苷脱氨酶 脑脊液 结核性脑膜炎 Adenosine deaminase Cerebrospinal fluid Tuberculous meningitis
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