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儿童嗜血细胞综合征2例 被引量:1

Report of 2 cases of hemophagocytic syndrome in children
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摘要 嗜血细胞综合征(hemophagocytic syndrome,HPS),又称噬血细胞淋巴组织细胞增生症(hemophagocytic lymphohistiocytosis,HLH),是单核/巨噬系统反应性疾病,以组织细胞良性、大量增生,伴有明显的吞噬血细胞现象为特征。
机构地区 武警总医院儿科
出处 《武警医学院学报》 CAS 2010年第12期1020-1021,共2页 Acta Academiae Medicinae CPAPF
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参考文献8

  • 1Bettinelli A,Maccario R,Clementi R,et al.Hemophagocytic lymphohistiocytosis in a patient with deletion of 22q 11.2[J].Am J Med Genet,1999,87(4):329-330.
  • 2Su IJ.Perspectives on the pathogenesis and therapy of hemophagocytic syndrome[J].J Formos Med Assoc,2008,107(4):277-280.
  • 3吴润晖,马晓莉.儿童噬血细胞性淋巴组织细胞增生症的诊断标准[J].实用儿科临床杂志,2009,24(15):1211-1213. 被引量:6
  • 4Wang Z,Chen X,Wu L,et al.Significance of hemopha gocytosis in diagnosis of hemophagocytic lympho histiocytosis[J].Zhongguo Shi Yan Xue Ye Xue Za Zhi,2009,17(4):1064-1066.
  • 5Mazodier K,Marin V,Novick D,et al.Severe imbalance of IL-18/IL-18BP in patients with secondary hemophagocytic syndrome[J].Blood,2005,106(10):3483-3489.
  • 6Olin RL,Nichols KE,Naghashpour M,et al.Successful use of the anti-CD25 antibody daclizumab in an adult patient with hemophagocytic lymphohistiocytosis[J].Am J Hematol,2008,83(9):747-749.
  • 7Kaya Z,Ozt u rk C,G u rsel T,et al.Spontaneous resolution of hemophagocytic syndrome and disseminated intravascular coagulation associated with Parvovirus B19 infection in a previously healthy child[J].Jpn J Infect Dis,2005,58(3):149-151.
  • 8Veerakul G,Sanpakit K,Tanphaichitr VS,et al.Secondary hemophagocytic lymphohistiocytosis in children:an analysis of etiology and outcome[J].J Med Assoc Thai,2002,85(Suppl 2):530-541.

二级参考文献14

  • 1仇佳晶,魏珉.幼年特发性关节炎全身型并发巨噬细胞活化综合征一例[J].中华儿科杂志,2005,43(11):874-875. 被引量:6
  • 2Kogawa K, Kee SM, Villanueva J, et al. Perforin expression in cytotoxic lymphocytes from patients with hemophagocytic lymphohistiocytosis and their family members [ J ]. Blood, 2002,99 ( 1 ) : 61 - 66.
  • 3Arico M, Imashuku S, Clementi R, et al. Hemophagocytic lymphohistiocytosis due to germline mutations in SH2D1A the X - linked lymphoproliferative disease gene[ J ]. Blood,2001,97 (4) : 1131 - 1133.
  • 4Arico M, Bettinelli A, Maccario R, et al. Hemophagocytic lymphohistioctyosis in a patient with deletion of 22q11, 2 [ J ]. Am J Med Genetics, 1999,87 (4) :329 - 330.
  • 5Arico M, Imashuku S. Hemaophagocytic lymphohistiocytosis due to germline mutations in SH2DIA, the X - linked lymphoproliferative disease gene[ J]. Blood,2001,97(4) :1131 - 1133.
  • 6Jordan MB, Hildeman D, Kappler J, et al. An animal model of hemophagocytie lymphohistiocytosis(HLH) :CD8 + Tcells and interferon gamma are essential for the disorder[ J]. Blood,2004,104 ( 3 ) :735 - 743.
  • 7Schneider EM, Lorenz I, Muller - Rosenberger M, et al. Hemophagocytic lymphohistocytosis is associated with deficiencies of cellular cytolysis but normal expression of transcripts relevant to killer - cell - induced apoptosis [ J ]. Blood,2002,100 ( 8 ) :2891 - 2898.
  • 8Groin AA, Villanueva J, Lee S, et al. NK cell dysfunction in patients with systemic onset juvenile rheumatoid arthritis and macrophage activation syndrome [ J 3. J Pediatr,2003,142 ( 3 ) :292 - 296.
  • 9Wulffraat NM, Rijkers GT, Elst E, et al. Reduced perforin expression in systemic onset juvenile idiopathic arthritis is restored by autologous stem cell transplantation [ J ]. Rheumatology (Oxfond), 2003,42 ( 2 ) : 375 - 379.
  • 10Abbas AA, Tapp HE, Rice MS, et al. Familial hemophagocytic lymphohistocytosis : A review of six cases [ J ]. Hematology, 2004,7 ( 2 ) : 233 - 239.

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