摘要
目的:探讨生脉注射液联合低分子量肝素钠(LMWH)治疗冠状动脉粥样硬化性心脏病(CAHD)不稳定心绞痛(UA)的临床疗效。方法:将70例UA患者随机分为治疗组(n=35)和对照组(n=35)。两组均给予吸氧、卧床休息、调降脂、阿司匹林、β受体阻滞剂、血管紧张素转换酶抑制剂/血管紧张素受体阻滞剂(ACEI/ARB)、单硝酸异山梨酯及按需硝酸甘油片舌下含服等常规治疗,治疗组同时加用LMWH腹壁皮下注射,12小时1次,连用7d;生脉注射液静滴,每目1次,连用10天。结果:治疗组与对照组相比,治疗后心绞痛发作频率下降,心绞痛持续时间减少(P<0.01)。治疗组临床疗效及心电图疗效与对照组相比差异有统计学意义(P<0.05)。结论:生脉注射液联合LMWH治疗UA具有疗效显著、安全可靠、见效快、疗程短、毒副作用小等诸多优点。
Objective： To explore the clinical curative effect of shengmai injection and low molecular weight heparin sodium（LMWH）in coronary atherosclerotic heart disease （CAHD） unstable angina （UA）.Methods： Patients with UA （ n = 70） were randomly divides into the treatment group （n = 35） and the comparison group （n = 35）. The two groups received oxygen, stay in bed, transfer lipid-lowering, aspirin, 13 blockers, angiotensin converting enzyme inhibitors / angiotensin receptor blockers （ACEI / ARB）, one nitrate and demand of isosorhide sublingnal nitroglycerin tablets, conventional treatment group added in the abdominal subcutaneous injection of LMWH, 12 hours a time, once a 7d; shengmal injection, iv 1, once every 10 days.Results：Treatment group compared with the control group after treatment decreased angina frequency, angina reduced the duration（P〈0.01 ）. The clinical therapeutic efficacy and ECG compared with the control group significantly （P〈0.05）.Conelusion：Shengmai injection and LMWH treatment of UA has a significant effect, safe, reliable, quick, short course of treatment, drug side effects and many advantages.
出处
《中国医药导刊》
2010年第11期1948-1949,共2页
Chinese Journal of Medicinal Guide
