摘要
目的:优化中药复方喷膜剂的提取工艺。方法:采取正交试验法设计并用HPLC法进行测定。结果:最佳工艺提取条件为A3B1C2D3,即药材加水10倍量,提取0.5h,分3次提取,醇沉最佳工艺的质量分数为80%乙醇。结论:经验证该实验优选得到的工艺稳定、工艺可行。
Objective:To research the optimume extracting conditions for Chinese medicine consperg film. Methods:The orthogonal experimental design and HPLC method were used.Results:According to the results of the orthogonal experiment,the optimum process was as follows:extracting solvent used water,0.5h each time, 10 times solvent,extraction for 3 times.The optimum alcohol precipitation process was as follows:80% precipitation concentration.Conclusion:The process is stable and highly efficient.
出处
《中国医药导刊》
2010年第12期2184-2185,共2页
Chinese Journal of Medicinal Guide
基金
国家中医药管理局新药开发专项课题(D1X038A)
关键词
正交试验
绿原酸
大黄素
大黄酚
Orthogonal design
Chlorogenic Acid
Emodin
Chrysophanol