摘要
目的:优化丹参总酚酸动态循环提取的工艺。方法:以丹参总酚酸的含量为指标,考察丹酚酸动态提取过程中温度、粒径、加水量、溶剂循环量、提取时间对提取效率的影响,并采用正交试验设计方法研究各参数对提取的影响。结果:丹参总酚酸动态循环提取的最佳方法为温度T为80℃,颗粒粒径为4 mm,循环量V为30 L.h-1,加水量S为10倍,提取时间150 min。结论:动态循环提取法与静态煎煮法相比较,能够提高丹参总酚酸的提取效率,减少溶剂消耗,节约能耗并降低后处理负担。
Objective： To optimize the dynamic extraction process of salvianolic acids.Method： Salvianolic acids was selected as index.The effects of extraction temperature,granularity,solvent multiple,circle value and extraction time were studied on the process of dynamical extraction.The orthogonal experiment was employed to investigate the influence of different parameters.Result： The optimal extracting method of salvianolic acids was as follows： temperature was 80 ℃,granularity was 4 mm,circle value was 30 L·h-1,solvent multiple was 10 times and extraction time was 150 min.Conclusion： By comparison to static extraction,dynamic extraction can improve the extraction efficiency,reduce the solvent and energy consumption,as well as lower the burden of post-processing.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2010年第22期2976-2979,共4页
China Journal of Chinese Materia Medica
基金
上海市国际合作基金项目(08520750300)
关键词
丹参总酚酸
动态提取
提取工艺
正交设计
salvianolic acids； dynamic extraction； orthogonal experiment
