摘要
目的:探讨治疗早期肾功能不全的有效途径。方法:选择我院104例早期肾功能不全患者,采用随机方法分为两组,对照组50例常规降糖、降压及调脂、优质低蛋白饮食等治疗,单用舒血宁。治疗组54例在对照组的治疗基础上应用舒血宁与前列地尔联合治疗,14日为1个疗程。结果:舒血宁与前列地尔联合治疗能有效降低尿微量白蛋白排泄率(UAER)及24 h尿蛋白定量,与对照组比较有显著性差异(P<0.05)。结论:舒血宁与前列地尔联合治疗早期肾功能不全有显著疗效。
Objective:To explore the effective treatment for early renal insufficiency.Methods:A total of 104 cases with early renal insufficiency were randomly divided into two groups.Fifty cases in control group were treated by conventional hypoglycemic therapy,hypotensive therapy,lipid-regulatory drugs,high quality low protein diet and Shuxuening alone.Fifty-four cases in treatment group were treated by combined therapy with Shuxuening and alprostadil with 14 days for a course.Results:The combined therapy with Shuxuening and alprostadil can significantly decrease urinary albumin excretion(UAER) and 24-hr urine protein(P0.05).Conclusions:The combined therapy with Shuxuening and alprostadil is effective on treating early renal insufficiency.
出处
《海南医学院学报》
CAS
2010年第12期1610-1612,共3页
Journal of Hainan Medical University
基金
海南医学院科研基金资助学报项目(0020100435)~~
关键词
前列地尔
舒血宁
肾功能不全
早期
疗效
Alprostadil
Shuxuening
Renal insufficiency
Early
Efficiency