摘要
目的:探讨幽门螺旋杆菌(Helicobacter pylori,HP)感染和血清胃蛋白酶原(Pepsinogen,PG)之间的关系。方法:分别对126例HP阴性组、94例HP弱阳性组、201例HP阳性组和97例治疗转阴组进行血清胃蛋白酶原PGⅠ、PGⅡ测定。结果:HP阳性组与阴性对照组比较血清PGⅠ及PGⅠ/PGⅡ水平有显著性差异(P<0.05)。阳性组与治疗转阴组比较血清PGⅠ及PGⅠ/PGⅡ水平有显著性差异(P<0.05)。弱阳性组与阴性对照组,弱阳性组与治疗转阴组之间比较PGⅠ及PGⅠ/PGⅡ水平没有显著性差异(P>0.05)。治疗转阴组与阴性对照组比较PGⅠ及PGⅠ/PGⅡ水平没有显著性差异(P>0.05)。结论:血清PGⅠ、PGⅡ水平与幽门螺旋杆菌感染密切相关。血清PGⅠ及PGⅠ/PGⅡ水平可作为HP根除效果的评价指标。
Objective： To study the relationship between serum pepsinogen and helicobacter pylori.Methods： Serum psinogenpeⅠ（PGⅠ）and psinogenpeⅡ（PGⅡ） were detected in 126 normal persons,94 persons with anti-HP antibody（IgG） weakly positive,201 persons with anti-HP antibody（IgG） positive and 97 cured case.Results： There was the remarkable difference in serum PGⅠand PGⅠ/ PGⅡ positive group and the control group（P0.05）.Serum PGⅠand PGⅠ/ PGⅡ in the positive group and the cured group showed the significant difference（P0.05）,while there was no difference in serum PGⅠand PGⅠ/ PGⅡ weakly positive group and the control group,and in weakly positive group and the cured groups（P0.05）.Serum PGⅠand PGⅠ/ PGⅡ levels in cured case group showed no significant differences compared to those in the control group（P0.05）.Conclusion： Serum psinogenpeⅠ（PGⅠ）and psinogenpeⅡ（PGⅡ） levels are closely related with anti-HP IgG,serum psinogenpeⅠ（PGⅠ）and psinogenpeⅡ（PGⅡ） level are the indexes of HP cured case.
出处
《河南大学学报（医学版）》
CAS
2010年第4期281-282,共2页
Journal of Henan University:Medical Science
