摘要
目的探讨静脉注射不同剂量地塞米松治疗外伤性蛛网膜下腔出血(tSAH)所致头痛的临床疗效。方法将78例外伤性蛛网膜下腔出血患者分别静脉给予常规剂量(治疗组,n=38例)及大剂量(对照组,n=40例)地塞米松,观察头痛改善情况,评价其疗效。结果治疗组头痛缓解有效率92.1%,对照组为95.0%,2组有效率差异无统计学意义(P>0.05)。结论伤后地塞米松静脉给药可有效缓解tSAH后头痛,且其疗效未发现剂量依赖性。
Objective To investigate therapeutic effects of different doses hexadecadrol by intravenous injection on headache caused by simple traumatic subarachnoid hemorrhage （SAH）. Methods Seventy-eight patients were randomly divided into two groups which were received regular dose （treatment group, 38 cases ） and large dose （control group, 40 cases） hexadecadrol by intravenous injection respctively. The effectiveness was assessed according to information of headache. Results The total effective rate of releasing headache was 92.1% in treatment group, 95% in control group. There was no statistic difference between the two groups （P 〉 0.05）. Conclusion Hexadecadrol by intravenous injection can release headache caused by SAH. And the therapeutic effect has no dose-respense relationship.
出处
《海军医学杂志》
2010年第4期333-335,共3页
Journal of Navy Medicine
