摘要
目的:对中药迷迭香Rosmarinus officinalis L.的化学成分进行研究。方法:采用硅胶、凝胶柱色谱等方法进行分离纯化,根据理化性质和NMR波谱数据进行结构鉴定。结果:分离得到8个化合物,分别鉴定为β-谷甾醇(β-sitosterol,1)、4′,5-二羟基-7-甲氧基黄酮(4′,5-dihydroxy-7-methoxyflavone,2)、熊果醇(uvaol,3)、3,5-二羟基-7,3′,4′-三甲氧基黄酮(3,5-dihydroxy-7,3′,4′-trimethoxyflavone,4)、5-羟基-4′,7-二甲氧基-6-甲基黄酮(5-hydroxy-4′,7-dimethoxy-6-methylflavone,5)、槲皮素(quercetin,6)、芦丁(rutin,7)、阿魏酸(ferulicacid,8)。结论:化合物2、4、5为首次从该属植物中分离得到。
Objective： To isolate the chemical constituents from Rosmarinus officinalis L. and identify their structures. Methods： The compounds were isolated by chromatography on silica and gel column, and their structures were identified by the physico-chemical properties and NMR spectral analysis. Results： Eight compounds were obtained and identified as/3-sitosterol （ 1 ）, 4＇, 5 -dihydroxy -7 -methoxyflavone （ 2 ）, uvaol （ 3 ）, 3,5 -dihydroxy -7,3＇, 4＇ - trimethoxyflavone （4）, 5 -hydroxy -4＇, 7 -dimethoxy -6 -methylflavone （ 5 ）, quercetin （ 6 ）, rutin （ 7 ）, ferulic acid （ 8 ）, respectively. Conclusion：Compounds 2,4 and 5 were obtained from this genus for the first time.
出处
《中国现代中药》
CAS
2011年第1期23-25,共3页
Modern Chinese Medicine
关键词
迷迭香
化学成分
结构鉴定
Rosmarinus officinalis L.
Chemical constituents
Structural identification
