摘要
目的观察阿维A联合紫外线治疗寻常型银屑病的临床疗效。方法选取寻常型银屑病患者106例,随机分为两组,对照组53例给予常规窄波紫外线治疗,治疗组53例在对照组基础上联合使用阿维A口服治疗,观察两组治愈率及不良反应情况。结果治疗组总有效率(92.4%)与对照组治疗效果(66.0%)的差异有统计学意义(P<0.05);两组不良反应发生率差异亦有统计学意义(P<0.05)。结论阿维A联合紫外线治疗寻常型银屑病能够起到较好的治愈效果,同时剂量过高会引起皮肤干燥,瘙痒,脱屑,肝肾功能异常等不良反应发生。因此合理控制阿维A剂量的情况下合理使用阿维A联合紫外线是临床上治疗寻常型银屑病的有效方法。
Objective To observe the clinical efficacy of acitretin combined with ultraviolet irradiation for the treatment of psoriasis vulgaris. Methods 106 patients with psoriasis vulgaris selected were randomly divided into two groups, 53 patients received conventional narrow band ultraviolet therapy in control group, based on the control group 53 patients in treatment group were given the oral acitretin treatment, the cure rates and adverse reactions were observed. Results The total effective rate was 92.4% in treatment group, 66.0% in control group, there was statistically significant difference （P〈0.05）; adverse reaction rates between the two groups were also statistically significant （P〈0.05）. Conclusion Acitretin combined with ultraviolet irradiation for the treatment of psoriasis vulgaris has better healing effect, while high doses can cause dry skin, itching, scaling, liver and kidney dysfunction and other adverse reactions. Therefore under the circumstance of reasonable acitretin control the reasonable use of acitretin combined with ultraviolet irradiation for the treatment of psoriasis vulgaris is the clinically effective method.
出处
《临床医学工程》
2011年第2期219-220,共2页
Clinical Medicine & Engineering
关键词
阿维A
紫外线治疗
寻常型银屑病
临床疗效
Acitretin
Ultraviolet treatment
Psoriasis vulgariss
Clinical efficacy
