摘要
糖尿病肾病是终末 期肾功能衰竭的重要因素之一,其确切发病机制尚未完全阐明。本文重点介绍了肾组织糖代谢紊乱、脂代谢紊乱、高血压、血管活性物质、生长因子、反应氧代谢产物及遗传因素在糖尿病肾病发生、发展中的作用。
Diabetic nephropathy
is one of important causes for end -stage renal disease. At present, the ex-act mechanism underlying its pathogen-
esis has not been fully understood. The article emphasized on introducmg roles of glucose metabolism disorder, lipid metabolism disorder, hypertension, va-soactive substance, growth factor, reac-tive oxygen intermediates as well as ge-netic factor in development or progres-sion of diabetic nephropathy
关键词
糖尿病
肾病
糖基化产物
蛋白激酶C
diabetic nephropathy, glycation product, protein kinase C, vasoactive substance, growth factor, progress
