摘要
目的探讨糖皮质激素性白内障的临床特点。方法分析内江市中医院78例激素性白内障患者（155眼）使用激素的原因,晶体混浊程度与用药时间、视力的关系。结果全身用药15例、局部用药63例;用药时间小于12个月者89眼,12个月者66眼。随着用药时间的增加,晶体混浊程度Ⅰ级、Ⅱ级所占比例降低,而Ⅲ级、Ⅳ级比例增加,Ⅰ级、Ⅲ级差异具有统计学意义（P〈0.05）。视力小于0.4组中Ⅲ级比例最高;0.4-1.0组中以Ⅰ级、Ⅱ级为主;〉1.0组中Ⅰ级比例最高,视力小于0.4组与0.4-1.0组、〈0.4组与〉1.0组差异具有统计学意义（P〈0.05）。结论使用糖皮质激素时间越长,剂量越大,激素性白内障的程度越重,视力越差。使用糖皮质激素时要随时警惕激素性白内障的发生,定期检查眼部。
Objective To investigate the clinical features of glucocorticoid induced cataracts.Methods To analyse the reasons of using hormone in 78 cases of glucocorticoid induced cataract in our hospital（155 eyes）.To explore the relationship between the time of medication,visual acuity and crystal turbidity.Results 15 cases were systemic administration.63 cases were local administration.The therapeutic time was shorter than 12 months in 89 cases and longer than 12 months in 66 cases.With the time increasing,the proportion of the I and II level of crystal turbidity was decreased.But the proportion of the Ⅲ and Ⅳ level of crystal turbidity was increased.The difference of the Ⅰ and Ⅲ level had statistically significance（P0.05）.The proportion of the III level was the highest in the visual acuity 0.4 group.The I and II level were major in the visual acuity 0.4-1.0 group.The proportion of the I level was the highest in the visual acuity 1.0 group.The difference was statistically significant between the visual acuity 0.4 group and the visual acuity 0.4-1.0 group.The difference was statistically significant between the visual acuity 0.4 group and the visual acuity 1.0 group.Conclusion The degree of crystal turbidity could be greater and the visual acuity could be worse when the time of using the hormone is longer and the dose is greater.We must be alert of glucocorticoid induced cataract and take regularly eye-checking when using gluoocorticoid.
出处
《检验医学与临床》
CAS
2011年第3期297-298,共2页
Laboratory Medicine and Clinic
关键词
激素
白内障
晶体
hormone
cataract
crystal
