摘要
目的分析干化学法和湿化学法测定血清肌酐的相关程度,探讨两种方法能否共用1个参考区间。方法随机收集80份血清标本,分别用干化学法和湿化学法测定血清肌酐含量,分析结果的相关性。以湿化学法为参考,所得回归方程校正干化学分析仪参数,再用两种方法分别测定血清肌酐,分析参数改变前后两种方法间测定结果差异无统计学意义。结果参数改变前,两种方法检测肌酐相关性良好,相关系数r=0.9924,但是方法间结果的预期偏差(SE)是27.666,大于允许偏差(EA)26.550;校正参数后,两种方法检测肌酐相关性良好,r=0.9949,SE=3.2972,小于EA/2。结论干化学法和湿化学法测定血清中肌酐浓度相关性良好,通过校正参数后可共用1个参考区间。
Objective To judge the correlation of serum creatinine by dry chemical and liquid chemical analysis, and decide whether these two methods can share a reference interval. Methods 80 serum samples were randomly collected and applyed dry chemical and liquid chemical method to measure serum creatinine levels,and analyse the correlation between the two mehtod. We detected the serum creatinine level by these two method after the anaysis parameters were changed. Results Before changes in the parameters,Creatinine level by the two methods correlated well（r=0. 992 4）, However, the results between the expected to bias（SE） of two methods is 27. 666 ,greater than the allowable deviation（EA）26.55. After parameters calibration,these two methods of ereatinine correlated well,r= 0. 994 9, SE--3. 297 2, which is less than EA/2. Conclusion Dry chemical and liquid chemical analysis have good correlation in serum creatinine concentration, they can share the universal reference interval after pa/ameters calibration.
出处
《国际检验医学杂志》
CAS
2011年第1期34-35,共2页
International Journal of Laboratory Medicine
关键词
化学
分析
参考值
肌酐
creatinine
dry chemical
reference interval
