摘要
考察了溴化N-烷基吡啶存在下的2'-羟基查耳酮碱催化环化反应及动力性质。结果表明,溴化正丁基吡啶能有效促进NaOH催化2'-羟基查耳酮转化为黄烷酮,在室温下反应2 h,黄烷酮产率达89.4%;碱催化环化反应为一级反应,当溴化正丁基吡啶作增敏剂时,该反应的表观活化能将从161.9 KJ/mol降至18.07KJ/mol。
The cyclization reaction and kinetic character of 2′-hydroxychalcone under alkaline with N-alkylpyridinium bromide had been researched.The results showed that n-butylpyridinium bromide could effective enhance the sodium hydroxide to catalyze 2′-hydroxychalcone converting into flavanone.When the reaction temperature was 20℃ and reaction time was 2 h,the yield of flavanone production was 89.4%.The cyclization reaction was first reaction.The reaction activity energy was decreased from 161.9 KJ/mol to 18.07 KJ/mol with n-butylpyridinium bromide as sensitizer.
出处
《化学研究与应用》
CAS
CSCD
北大核心
2011年第2期199-203,共5页
Chemical Research and Application
基金
教育部科学技术研究重点项目(208119)资助
重庆工商大学研究生创新科研项目(yjscxx2009-07)资助
