摘要
目的探讨加替沙星联合盐酸氨溴索治疗老年急性肺炎的临床疗效和安全性。方法将100例患者随机分成两组,观察组和对照组各50例,观察组应用加替沙星联合盐酸氨溴索治疗,对照组应用左氧氟沙星联合盐酸氨溴索治疗,观察并比较两组治疗前后症状、细菌学、药敏情况与并发症。结果观察组治疗有效率、细菌清除率、不良反应发生率分别为92.00%、94.34%、8.00%,对照组治疗发生率分别为74.00%、78.85%、12.00%,两组治疗比较差异均有统计学意义(P<0.05),不良反应发生率比较无统计学意义(P>0.05)。结论加替沙星联合盐酸氨溴索治疗老年急性肺炎具有较好的疗效和安全性,值得临床推广应用。
Objective To explore the clinical effect and safety of gatifloxacin and ambroxol hydrochloride treating acute pneumonia in elderly patients.Methods 100 patients with acute pneumonia in elderly patients were randomly divided into the intervention group（50 cases） and control group（50 cases）.The intervention group were treated with gatifloxacin and ambroxol hydrochloride,the control group were treated with levofloxacin and ambroxol hydrochloride;Symptoms、bacteriology and drug sensitiveness of two groups were observed respectively before and after treatment.Results The effective rate、bacterial clearing rate and occurrence of the adverse reaction in the intervention group were 92.00%、94.34% and 8.00% respectively,in the control group were 74.00%、78.85% and 12.00% respectively,the effective rate and bacterial clearing rate were significantly（P0.05）,occurrence of the adverse reaction was no significantly（P0.05）.Conclusion The gatifloxacin and ambroxol hydrochloride treating acute pneumonia in elderly patients is more effective and safely,and hence is worthy of being recommended in clinical practice.
出处
《临床肺科杂志》
2011年第3期363-364,共2页
Journal of Clinical Pulmonary Medicine
关键词
加替沙星
左氧氟沙星
盐酸氨溴索
急性肺炎
老年
gatifloxacin
levofloxacin
ambroxol hydrochloride
acute pneumonia
elderly
