摘要
目的观察金因肽(外用重组人表皮生长因子,rhEGF)治疗手足口病口腔溃疡的疗效。方法将138例手足口病并发口腔溃疡患儿随机分成对照组及治疗组。两组均采用抗病毒,对症支持治疗。治疗组69例,金因肽局部喷药;对照组69例,给予碘甘油局部涂药。以创面愈合时间及疼痛消失时间为考察指标,比较金因肽和碘甘油治疗手足口病口腔溃疡的疗效。结果两组比较,金因肽组溃疡愈合时间和进食改善到正常的时间显著缩短,结果具有统计学意义。结论金因肽在加快儿童手足口病并口腔溃疡的愈合和改善进食情况方面具有一定效果。
Objective To evaluate the effect of recombinant human epidermal growth factor（rhEGF）for hand-foot-mouth disease（HFMD）. Methods One hundred and thirty-eight children suffered from HFMD were divided into a treatment group and a control group randomly.Two groups were treated with anti-virus and support treatment. The treatmen group（69 cases）was given rhEGF and control group（69 cases）was given iodine glycerin. The healing time of oral ulcer wound and the ache disappear time were recorded. Results The average time of oral ulcerations healing and recovery of eating in treatment group was significantly shorter than that of control group（P0.05）. Conclusion The recombinant human epidermal growth factor（rhEGF）have some effects on hand foot and mouth disease in children. The rhEGF could fasten the healing of oral ulcerations and the recovery of eating.
出处
《中国实用医药》
2011年第2期13-14,共2页
China Practical Medicine
关键词
手足口病
儿童口腔溃疡
表皮生长因子
治疗
Hand-foot-mouth disease（HFMD）
Child oral ulcer
Recombinant human epidermal growth factor（rhEGF）
Therapy
