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黑色素性神经外胚瘤临床病理学观察 被引量：2

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摘要 目的探讨黑色素性神经外胚瘤（MNT）的临床病理特征和鉴别诊断。方法收集2例MNT资料并复习文献。结果MNT多发生于1岁内的婴儿，个别年龄较大。上下颌骨多见。肿瘤由含色素的上皮样细胞和小圆形神经母细胞样细胞构成。上皮样瘤细胞常表达Vimentin、CK、EMA、HMB45，小圆形神经母细胞样瘤细胞表达CD57、Syn，两类瘤细胞S-100通常阴性。结论MNT是良性肿瘤，起源于神经外胚层，很罕见，具有典型的临床特征和组织学形态。需要警惕的是婴儿MNT呈浸润性生长，速度惊人，溶骨性破坏，术后复发率高。
作者 赵燕 于鸿 宋振缃
机构地区 江苏省泰州市人民医院病理科
出处 《肿瘤研究与临床》 CAS 2011年第1期58-60,共3页 Cancer Research and Clinic
关键词 神经外胚瘤 黑色素 婴儿 免疫组织化学
分类号 R739.4 [医药卫生—肿瘤]
  • 相关文献

参考文献8

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二级参考文献17

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共引文献4

同被引文献22

  • 1王伟,刘国辉.婴儿黑色素性神经外胚层瘤的CT与MRI诊断[J].中华临床医师杂志（电子版）,2011,5(10):3071-3073. 被引量：5
  • 2张忠德,奚政君,吴湘如,殷敏智,张凤英.婴儿头颅黑色素性神经外胚层瘤2例[J].诊断病理学杂志,2005,12(4):316-316. 被引量：2
  • 3Tan O,Atik B,Ugras S.Melanotic neuroectodermal tumor in a newborn[J].Int J Peditar Otorhintaryngol,2005,69(10):1441-1444.
  • 4Pantanowitz L,Galan A,Gang DL,et al.Diagnostic cytologic features of an epididymal melanotic neuroectodermal tumor of infancy present in scrotal fluid:a case report[J].Acta Cytol.2006,50(4):460-465.
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  • 10Jash PK, Roy C, Chatterjee K. Melanotic neuro-ectodermal tumour of infancy[ J]. J Indian Med Assoc, 2012,110 (8) :578, 583.

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肿瘤研究与临床
2011年 第1期

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