期刊文献+

宫颈液基细胞学联合人乳头状瘤病毒检测筛查宫颈病变临床分析 被引量:5

原文传递
导出
摘要 目的探讨宫颈液基细胞学(TCT)联合13种高危型人乳头状瘤病毒(HR-HPV)检测对宫颈疾病的筛查能力。方法对2002年6月至2010年5月于我院门诊进行宫颈疾病筛查患者2800例,进行TCT和13种HR-HPV(以下简称HPV)检测,对TCT检查异常、HPV(+)及阴道镜下怀疑病变的324例患者行组织活检,以病理检查结果为标准。结果筛查者平均年龄38.4岁,11.6%的患者TCT≥不典型鳞状细胞(ASCUS),33.1%的患者HPV感染(+)。在阴道镜下多点活检结果:TCT和HPV均(-)者,无高度病变的发生;TCT(-)和HPV(+)者中,≥CINⅡ级的检出率为11.8%(4/34),TCT异常和HPV(+)同时存在的病例中,≥CINⅠ级的检出率最高32.7%(76/232);仅TCT异常而HPV(-)者25%(12/48),且12例均为CINⅡ级,无原位癌和浸润癌的发生。结论 TCT联合HPV检测是宫颈疾病筛查的有效方法。
作者 周乃菊
出处 《临床医学》 CAS 2011年第1期78-80,共3页 Clinical Medicine
  • 相关文献

参考文献3

二级参考文献15

  • 1Syrjanen S,Shabalova IP,Petrovichev N,et al.Human papillomavirus testing and conventional Pap smear cytology as optional screening tools of women at different risks for cervical cancer in Countries of the former Soviet Union.J Low Genit Tract Dis,2002,6:97-110.
  • 2Bosch FX,Manos MM,Munoz N,et al.Prevalence of human papillomavirus in cervical cancer:a worldwide perspective.International biological study on cervical cancer (IBSCC) Study Group.J Natl Cancer Inst,1995,87:796-802.
  • 3Vizcaino AP,Moreno V,Bosch FX,et al.International trends in incidence of cervical cancer:Ⅱ.Squamous-cell carcinoma.Int J Cancer,2000,86:429-435.
  • 4Munoz N,Bosch FX,de Sanjose S,et al.Epidemiologic classification of human papillomavirus types associated with cervical cancer.N Engl J Med,2003,348:518-527.
  • 5Clavel C,Masure M,Bory JP,et al.Human papillomavirus testing in primary screening for the detection of high-grade cervical lesions:a study of 7932 women.Br J Cancer,2001,84:1616-1623.
  • 6Blumenthal PD,Gaffikin L,Chirenje ZM,et al.Adjunctive testing for cervical cancer in low resource settings with visual inspection,HPV,and the Pap smear.Int J Gynaecol Obstet,2001,72:47-53.
  • 7Kuhn L,Denny L,Pollack A,et al.Human papillomavirus DNA testing for cervical cancer screening in low-resource settings.J Natl Cancer Inst,2000,92:818-825.
  • 8Saslow D,Runowicz CD,Solomon D,et al.American cancer society guideline for the early detection of cervical neoplasia and cancer.CA Cancer J Clin,2002,52:342-362.
  • 9Sherman ME,Lorincz AT,Scott DR,et al.Baseline cytology,human papillomavirus testing,and risk for cervical neoplasia:a 10-year cohort analysis.J Natl Cancer Inst,2003,95:46-52.
  • 10Belinson J,Qiao YL,Pretorius R,et al.Shanxi province cervical cancer screening study:a cross-sectional comparative trial of multiple techniques to detect cervical neoplasia.Gynecol Oncol,2001,83:439-444.

共引文献175

同被引文献36

二级引证文献12

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部