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甜味觉受体及信号转导研究进展 被引量：1

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摘要 溶液中的甜味剂作用于味觉细胞相关受体分子,产生甜味觉信号,刺激相关神经中枢,使机体感受到甜味剂的存在。通过识别甜味剂,可以帮助人类找到提供能量的物质。甜味觉也能满足食欲,取得愉悦,过度食用甜味剂可导致肥胖,影响人体健康。了解甜味剂引起甜味觉的机理，寻找能够激发甜味觉低能量物质，对保护人体健康有重要意义。
作者 刘玉凤 柯杰 赵桂芝
机构地区 北京市大兴区人民医院口腔科 空军总医院口腔科
出处 《现代口腔医学杂志》 CAS CSCD 2011年第1期61-64,共4页 Journal of Modern Stomatology
关键词 信号转导 味觉受体 能量物质 人体健康 甜味剂 甜味觉 受体分子 味觉细胞
分类号 R33 [医药卫生—人体生理学]
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同被引文献32

  • 1姚金成,胡领,瞿延晖,赵绪元.辣椒素受体的研究概况[J].中国医院药学杂志,2004,24(12):771-773. 被引量：5
  • 2Ayako Koizumi, Asami Tsuchiya, Ken-ichiro Nakajima, et al. Human sweet taste receptor mediates acid-induced sweetness of miraculin[J]. Proc Nail Acad Sci USA,2011,108(40) :16819.
  • 3Sara Janssen, Jorien Laermans. Bitter taste receptors and α-gust- ducin regulate the secretion of ghrelin with functional effects on food intake and gastric emptying [ J ]. Proc Natl Acad Sci USA, 2011,108(5) :2094.
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  • 6Fariba M Assadi-Porter, Emeline L Maillet. Key amino acid resi- dues involved in multi-point binding interactions between brazzein, a sweet protein, and the T1R2-T1 R3 human sweet re- ceptor[J]. J Mol Biol,2010,398(4) :584.
  • 7Shinji Kataoka, Ruibiao Yang, Yoshiro Ishimaru. The candidate sour taste receptor, PKD2L1, is expressed by type Ⅲ taste cells in the mouse[ J]. Chem Senses,2008,33(3) :243.
  • 8Marlene F Shehata. Regulation of the epithelial sodium channel [ ENaC ] in kidneys of salt-sensitive Dahl rats: insights on alter- native splicing[J]. Int Arch Med,2009,2(28) :1.
  • 9Salazar H, Llorente I, Jara-Oseguera A, et al. A single N-termi- nal cysteine in TRPV1 determines activation by pungent com- pounds from onion and garlic[J]. Nat Neurosci,2008,11 : 255.
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现代口腔医学杂志
2011年 第1期

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