摘要
目的探讨乳腺癌前哨淋巴结活检(SLNB)技术的研究现状和进展。方法复习近年来国内、外的有关文献,对乳腺癌SLNB的定位、检取、状态评估、适应证和并发症进行分析与综述。结果乳腺癌SLNB能够准确定位、检取前哨淋巴结(SLN)。影像学检查和病理检测技术的发展有助于SLN状态的评估,SLNB的适应证正在不断扩大。该技术并发症少,能够准确判定腋窝分期,指导选择性的腋窝淋巴结清扫。结论 SLNB技术已成为乳腺癌外科治疗的重要手段,但其操作尚需进一步规范,以降低假阴性的发生;假阳性和有争议的适应证问题仍需继续关注。
Objective To summarize the current status and advances of sentinel lymph node biopsy（SLNB） technique in breast cancer.Methods The pertinent domestic and overseas literatures were reviewed and the localization,harvest,status assessment,indications,and complications of SLNB were analyzed.Results SLNB could accurately locate and pick out sentinel lymph node（SLN） in breast cancer.The development on imaging examination and pathological techniques promoted the assessment of SLN,and the indications of SLNB were expanding.The complication rate of SLNB was low and the technique could accurately predict axillary lymph node staging and direct selective axillary lymph node dissection.Conclusions SLNB has been an important method of surgical therapy in breast cancer,but the operation process needs to be further standardized to decrease the false negative rate.Continuative attentions shall be paid to the problems such as the false positive and controversial indications.
出处
《中国普外基础与临床杂志》
CAS
2011年第1期98-102,共5页
Chinese Journal of Bases and Clinics In General Surgery
关键词
乳腺癌
腋窝淋巴结清扫
前哨淋巴结活检
假阴性
假阳性
Breast cancer
Axillary lymph node dissection
Sentinel lymph node biopsy
False negative
False positive
