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Ghrelin基因多态性与多种疾病相关性研究进展 被引量:7

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摘要 Ghrelin是由胃分泌的一种激素,是迄今为止在体内发现的生长激素促分泌激素受体的内源性配体,其作用于下丘脑、垂体、肠道、胰腺、肾脏、性腺及胎盘等组织,发挥相应的生理学功能。研究发现,Ghrelin的单核苷酸多态性与人类多种疾病如肥胖症、糖尿病、心血管疾病、代谢综合征、精神分裂症等存在关联,本文就Ghrelin基因多态性研究进展作一综述。
出处 《新乡医学院学报》 CAS 2011年第1期119-122,共4页 Journal of Xinxiang Medical University
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  • 1Maahs DM, West NA, Lawrence JM, et al. Epidemiology of type ! diabe- tes[ J]. Endocrinol Metab Clin North Am ,2010,39 (3) :481 -497.
  • 2Bell RA, Mayer Davis EJ, Beyer JW,et al. Diabetes in non -Hispanic white youth: Prevalence, incidence, and clinical characteristics: The SEARCH for Diabetes in Youth Study[ J]. Diabetes Care ,2009,32 (sup- pl 2) :S102 - S111.
  • 3Zhang H, Xia W, Yu Q,et al. Increasing incidence of type i diabetes in children aged 0 - 14 years in Harbin, China ( 1990 - 2000 ) [ J ]. Prim Care Diabetes ,2008,2 ( 3 ) : 121 - 126.
  • 4Mackay D J, Temple IK. Transient neonatal diabetes mellitus type 1 [ J]. Am J Med Genet C Semin Med Genet,2010,154(3) :335 -342.
  • 5Pearson ER. Recent advances in the genetics of diabetes[ J]. Prim Care Diabetes ,2008,2 ( 2 ) :67 - 72.
  • 6Szypowska A, Skorka A. The risk factors of ketoacidosis in children with newly diagnosed type 1 diabetes mellitus[ J]. Pediatr Diabetes,2010,10 ( 11 ) : 1399 - 5448.
  • 7Yang L, Luo S, Huang G, et al. The diagnostic value of zinc transporter 8 autoantibody ( ZnTSA ) for type 1 diabetes in Chinese [ J ]. Diabetes Metab Res Rev ,2010 ,26( 7 ) :579 - 584.
  • 8Wenzlau JM, Frisch LM, Cardner T J, et al. Novel antigens in type 1 dia- betes : The importance of ZnT8 [ J ]. Curr Diab Rep, 2009,9 ( 2 ) : 105 - 112.
  • 9Hubcek JA, Bohuslavov R, Skodov Z, et al. Variants within the ghrelin gene association with HDL-choles- terol, but not with body mass index[J]. Folia Biologica (Praha), 2007,53 (6) : 202-206.
  • 10Pacifico L,Poggiogalle E,Costantino F, et al. Acylated and nonacylated gbrelin levels and their associations with insulin resistance in obese and normal weight chil- dren with metabolic syndrome[J]. Eur J Endocrinol, 2009,161 (6) : 861-870.

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