摘要
通过建立调强放射治疗计划中的笔束强度和模拟动力学系统中的粒子位置之间的联系,模拟动力学方法可以应用于解决调强放射治疗中的优化问题.本文研究了模拟动力学方法在肿瘤的临床调强放射治疗中的应用.研究表明,在引入软约束、硬约束和剂量体积约束等约束条件后,模拟动力学方法可以满足临床的调强放射治疗计划的要求.
By introducing the analogous relationship between the pencil beam intensity in intensity modulated radiotherapy and the atomic position in classical molecular dynamics system, the simulated dynamics algorithm can be used to deal with optimization problem occurring in intensity modulated radiothera- py. A study has been done by applying the simulated dynamics algorithm to several clinical intensity modulates radiotherapy cases. The results show that the simulated dynamics method can satisfy the clinical requirements by additionally employing the soft, hard and dose volume constraints.
出处
《四川大学学报（自然科学版）》
CAS
CSCD
北大核心
2011年第1期109-115,共7页
Journal of Sichuan University(Natural Science Edition)
基金
国家自然科学基金重点项目(10335050)
国家自然科学基金面上项目(10475059)
关键词
模拟动力学
调强放射治疗
适形放射治疗
simulated dynamics algorithm, intensity modulated radiotherapy, conform radiotherapy
