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Lignan glucoside from Sinopodophyllum emodi and its cytotoxic activity 被引量:6

Lignan glucoside from Sinopodophyllum emodi and its cytotoxic activity
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摘要 A new lignan glycoside was isolated from the n-butanol extract of the roots and rhizomes of Sinopodophyllum emodi.On the basis of spectral evidences,its structure was established and named as 4,5-didemethylpodophyllotoxin 7'-O-β-D-glucopyranoside. This compound showed cytotoxicity against four human cancer cell lines(Hela,K562,SH-SY5Y and CNE) in vitro. A new lignan glycoside was isolated from the n-butanol extract of the roots and rhizomes of Sinopodophyllum emodi.On the basis of spectral evidences,its structure was established and named as 4,5-didemethylpodophyllotoxin 7'-O-β-D-glucopyranoside. This compound showed cytotoxicity against four human cancer cell lines(Hela,K562,SH-SY5Y and CNE) in vitro.
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2011年第2期181-184,共4页 中国化学快报(英文版)
基金 supported by the Chinese National Natural Science Foundation(No.30973869) the Ministry of Science and Technology of China(No.2008BAC39B05) Foundation of Shannxi Provincial Education Department
关键词 Sinopodophyllum emodi BERBERIDACEAE 4 5-Didemethylpodophyllotoxin 7'-O-β-D-glucopyranoside CYTOTOXICITY Sinopodophyllum emodi Berberidaceae 4,5-Didemethylpodophyllotoxin 7'-O-β-D-glucopyranoside Cytotoxicity
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  • 1C.Q. Zhao, J. Huang, A. Nagatsu, et al. Chem. Pharm. Bull. 49 (2001) 773.
  • 2C.Q. Zhao, W. Cao, A. Nagatsu, et al. Chem. Pharm. Bull. 49 (2001) 1474.
  • 3C.Q. Zhao, A. Nagatsu, K. Hatano, et al. Chem. Pharm. Bull. 51 (2003) 255.
  • 4C.Q. Zhao, W. Cao, J. Huang, et al. J. Nat. Med. 55 (2001) 152.
  • 5Y.E Liu, C.Q. Zhao, H.X. Li, et al. Can. J. Physiol. Pharmacol. 88 (2010) 472.
  • 6Q.Y. Zhang, M. Jiang, C.Q. Zhao, et al. Toxicology 212 (2005) 45.
  • 7Y.L. Qi, E Liao, C.Q. Zhao, et al. Acta Pharmacol. Sin. 26 (2005) 1000.
  • 8A.J. Broomhead, EM. Dewick, Phytochemistry 29 (1990) 3839.

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