摘要
甘油脱水酶是微生物发酵法生产3-羟基丙醛和1,3-丙二醇过程中的关键限速酶.文中对甘油脱水酶的结构与功能、作用机制、基因工程研究等情况进行综述,探讨了甘油脱水酶的研究进展并提出一些建议.
Glycerol dehydratase(GDHt) is a key rate-limiting enzyme in the process of producing 3-hydroxypropionaldehyde(3-HPA) and 1,3-propanediol(1,3-PD) by microbial fermentation.In this paper,the research in the structure and functions,catalytic mechanism and genetic engineering of GDHt were reviewed.The research progresses of GDHt were also discussed and some suggestions were given in the end.
出处
《华侨大学学报(自然科学版)》
CAS
北大核心
2011年第2期125-129,共5页
Journal of Huaqiao University(Natural Science)
基金
国家高技术研究发展(863)计划项目(2006AA020103)
国家自然科学基金资助项目(20446004
20676048)
关键词
甘油脱水酶
生物转化法
结构功能
作用机制
基因工程
glycerol dehydratase
biotransformation
structure and functions
catalytic mechanism
genetic engineering