摘要
1 Science in the large-scale sequencing era Ten years ago, the first draft sequence assembly of the human genome was completed, bringing biomedical research one-step closer toward the goal of revolutionizing diagnosis, prevention, and treatment of human diseases. Recently, journalists from the journal Nature surveyed more than 1000 life scientists regarding this laudable aim, obtaining substantially negative responses.
1 Science in the large-scale sequencing era Ten years ago,the first draft sequence assembly of the human genome was completed [1],bringing biomedical research one-step closer toward the goal of revolutionizing diagnosis,prevention,and treatment of human diseases.Recently,journalists from the journal Nature surveyed more than 1000 life scientists regarding this laudable aim [2],obtaining substantially negative responses [3].However,almost all of those surveyed had been influenced,in one way or another,by the availability of the human genome sequence,and they also agreed with the notion that the 'sequence is the start.' The complexity of genome biology and almost every aspect of human biology is far greater than previously thought [4].
基金
supported by the Special Foundation Work Program(Grant No. 2009FY120100)
the National Key Technology Research and Development Program,Ministry of Science and Technology of China(Grant No. 2008BA164B02)