摘要
目的观察分析应用左旋布比卡因联合布托啡诺在产科术后硬膜外镇痛中临床疗效。方法选取2008年1月～2009年1月间择期剖宫产手术患者67例,随机分为治疗组34例和对照组33例,两组患者在年龄、体重、身高等各方面情况均无统计学差异(P>0.05)。手术结束前20min,对照组经L2～3硬膜外导管注入左旋布比卡因5ml,治疗组经L2～3硬膜外导管注入左旋布比卡因与布托啡诺复合液5ml。采用10cm视觉模拟评分表(10cmVAS)对患者镇痛效果进行评价。结果治疗组6h、12h、24h、36h镇痛效果与镇静效果均优于对照组,具有显著性差异(P<0.05);治疗组24h、36h舒适度优于对照组,具有显著性差异(P<0.05);两组6h、12h、24h、36h平均动脉压、心率无显著性差异(P>0.05),不具备统计学意义。结论左旋布比卡因联合布托啡诺应用于产科术后硬膜外镇痛中,镇痛效果、镇静效果、舒适度明显优于单纯使用左旋布比卡因治疗,可以有效缓解患者疼痛,适合于临床中推广应用。
Objective To observe and analyze the effects of levobupivacaine combinated with butorphanol postoperative epidural analgesia in obstetric clinical application. Methods 67 patients undergoing cesarean section in our hospital were recruited from January 2008 to January 2009, and randomly divided into treatment group （34 cases） and control group （33 cases）. The general status of the patients between the two groups, such as age, weight, height, etc., were no difference （P0.05）. Before 20mins from the end of surgery, patients in control group received 5ml levobupivacaine injection through epidural catheter by the L2~3, the treatment group received 5ml epidural injection of levobupivacaine-butorphanol composite liquid by the L2~3. Analgesia effects were evaluated by the 10cm visual analog scale（10cmVAS）. Results The sedative and analgesic effect of treatment group were better than control group after 6h, 12h, 24h and 36h post-surgery, respectively（P0.05）. After 24h, 36h, comfort degree in treatment group were better than the control group, with significant differences （P0.05）; mean arterial pressures, heart rates between two groups in 6h, 12h, 24h, 36h post surgery were no significant difference （P0.05）. Conclusion Using levobupivacaine combinated with butorphanol in obstetric epidural analgesia post-surgery, the analgesic effect, sedative effect, comfort degree are superior to receiving levobupivacaine alone. It might be alleviate pain effectively and suitable for clinical application.
出处
《当代医学》
2011年第8期10-11,共2页
Contemporary Medicine
关键词
左旋布比卡因
布托啡诺
术后镇痛
Levobupivacaine
Butorphanol
Obstetric epidural analgesia
