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原发性胆囊癌相关基因研究与分子靶向治疗进展 被引量:7

原发性胆囊癌相关基因研究与分子靶向治疗进展
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摘要 胆囊癌(gallbladder carcinoma,GBC)是胆道系统常见的恶性肿瘤,在消化道肿瘤中其发病率居第五位。由于胆囊癌早期诊断困难,预后极差,近年各国学者对胆囊癌的分子生物学异常进行了广泛而深入的研究,试图寻找胆囊癌的早期诊断分子标志和潜在的治疗靶点[1,2]。本文就胆囊癌已发现的一些重要分子事件、新近发现的相关基因及几个备受关注的分子治疗靶点进行重点阐述。
作者 闵军 林浩铭
出处 《中国实用外科杂志》 CSCD 北大核心 2011年第3期261-264,共4页 Chinese Journal of Practical Surgery
关键词 胆囊癌 基因研究 gallbladder carcinoma gene reasearch
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