摘要
目的:了解我院术前预防用抗菌药物选择是否符合"关于抗菌药物临床应用管理有关问题的通知("简称"通知)"的要求,使用是否合理,能否达到预防手术部位感染的目的。方法:通过我院抗菌药物查询系统,按手术部位分别统计、对比2008年1-6月和2010年同期我院Ⅰ类和Ⅱ类手术术前预防用抗菌药物的使用情况及临床效果。结果:执行"通知"规定以来,我院术前预防用抗菌药物的69.50%的手术能按"通知"规定合理选药。泌尿外科以外的手术喹诺酮类的使用比例从2008年的27.77%降至3.52%,差异有统计学显著性(P<0.05)。平均费用略有增加,手术部位感染率无统计学显著性差异(P>0.05),Ⅰ类手术切口感染率符合卫生部≤1.5%的要求。结论:我院术前预防用抗菌药物的使用趋于规范,但仍有不合理用药情况。
Objective：To explore the implementation status of hospital ＇Rule＇ on preoperative application of prophylactic antibiotics and the effectiveness of the rule in protecting the operation field from infection.Methods：By using the hospital inquiry system for antibiotics,preoperative uses of prophylactic antibiotics in incision type I and II operations were compared and analyzed for their use,and effectiveness was compared between January to June in 2008 and 2010 sorted by operation location.Results：In 2010,after the implementation of the ＇Rule＇,69.50% preoperative application of prophylactic antibiotics was normative.The use of quinolones as preoperative prophylactic antibiotics decreased dramatically except for urology department（P0.05）.The average expense increased slightly,and the infection rate in operation sites was the same（P0.05）.The nosocomial infection rate for operation of type I incision met the demand of no more than 1.5% which is issued by Ministry of Health.Conclusion：The prophylactic application of preoperative antibiotics is normative with few unreasonable cases.The ＇Rule＇ should be consistently reinforced.
出处
《中国新药杂志》
CAS
CSCD
北大核心
2011年第5期471-474,476,共5页
Chinese Journal of New Drugs
关键词
术前
预防
抗菌药物
用药情况
preoperative
prophylactic
antibiotic
implementation situation
