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腺苷脱氨酶及结核抗体在糖尿病合并肺结核诊断中的价值 被引量:5

Diagnostic Value of Adenosine Deaminase and Tuberculosis Antibody Detection in Diabetes Complicated with Pulmonary Tuberculosis
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摘要 目的评价腺苷脱氨酶和结核抗体检测用于辅助诊断糖尿病合并肺结核的价值。方法对116例糖尿病合并肺结核患者、133例糖尿病合并非结核肺部感染患者以及120例健康人群的血清腺苷脱氨酶(ADA)、结核抗体(TB-Ab)进行检测并分析。结果糖尿病合并肺结核患者血清ADA水平(22.7±7.3 u/L)和阳性率(70.3%)明显高于其它两组,均有显著性差异(P<0.01)。糖尿病合并肺结核患者TB-Ab阳性率(71.5%)较糖尿病合并非结核肺部感染患者(8.5%)和健康人群对照组(7.5%)有显著性差异(P<0.01)。结论 ADA和TB-Ab联合检测对于辅助诊断糖尿病合并肺结核特别是结核症状不典型的病例有一定价值。 Object To Evaluate value of adenosine deaminase(ADA) and tuberculosis antibody(TB-Ab) detection in diagnosis of diabetes complicated with pulmonary tuberculosis.MethodsSerum ADA,TB-Ab were detected among 116 patients with diabetes complicated with pulmonary tuberculosis,133 patients with diabetes without tuberculosis pneumonia and 120 health control.ResultsADA level(10.7±3.3u/L) and positive ratio(20.3%)in diabetes without tuberculosis l pneumonia is higher(P0.05) than normal controls(5.2±1.6u/L and 1.7%),and even higher(P0.01) in diabetes complicated with pulmonary tuberculosis(22.7±7.3u/L and 70.3%).They are significantly differ from each other.TB-Ab positive ratio in diabetes complicated with pulmonary tuberculosis(71.5%) is significant higher(P0.01) than individual without tuberculosis(7.5% in normal control and 8.5% in diabetes).And Serum ADA,TB-Ab both detected positive among patients with diabetes complicated with pulmonary tuberculosis,ADA level is 25.95±10.9 u/L.ConclusionSimultaneous detection of ADA and TB-Ab is valuable for diagnosis of diabetes complicated with tuberculosis,especially those with no classic tuberculosis.
出处 《临床肺科杂志》 2011年第4期544-545,共2页 Journal of Clinical Pulmonary Medicine
关键词 糖尿病合并肺结核 腺苷脱氨酶 抗体 结核 诊断 肺部感染 Diabetes complicated with tuberculosis Adenosine deaminase(ADA) Antibody tuberculosis(TBAb) Diagnosis pneumonia
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