摘要
目的探讨血清铁蛋白在评价噬血细胞综合征治疗效果中的意义。方法将12例确诊噬血细胞综合征患者按照转归分为存活组和死亡组,记录并分析治疗前后血清铁蛋白水平实验室指标变化。结果两组患者血清铁蛋白在治疗前后均存在统计学差异,其中存活组为P=0.025,死亡组P=0.037。结论血清铁蛋白水平变化提示噬血细胞综合征的活动度,是评价其治疗效果的重要指标。
Objective To study the clinical significance of serum ferritin in evaluation of treatment response in hemophagocytic syndrome.Methods Twelve patients diagnosed as hemophagocytic syndrome were divided into survival group and death group according to their therapeutic results,and their results of serum ferritin were recorded and compared before and after treatment.Results There was statistically significant difference in comparison with results of serum ferritin before and after treatment in patients of both groups（survival group P=0.025,death group P=0.037）.Conclusion The result of serum ferritin will probably indicate the activity of hemophagocytic syndrome,and detection of serum ferritin will be helpful in evaluation of the efficacy of treatment in patients with hemophagocytic syndrome.
出处
《临床和实验医学杂志》
2011年第5期333-334,337,共3页
Journal of Clinical and Experimental Medicine
基金
首都临床特色应用研究D101100050010005
首都医学发展基金2009-1032
