摘要
Objective：To observe the clinical effect of combined acupuncture and Chinese medicine for reflux esophagitis.Methods：120 cases with reflux esophagitis were randomly allocated into 4 groups,30 in each group,a group of combined acupuncture and Chinese medicine,a group of Chinese medicine,a group of acupuncture and agroup of Westem medication（Omeprazole Enteric-coated Capsules）.Cases in the four groups were treated 60 d as one course of treatment.The plasma gastrin and motilin levels in all groups were measured before and one course after treatment for effect evaluafion.Results：There were no inter-group statistical differences of plasma gastrin and motilin levels before treatment.The plasma gastrin and motilin levels in all groups were significantly elevated after treatment（P〈0.01）.The group of combined acupuncture and Chinese medicine showed a significantly higher level than the Western medication and Chinese medicine group （P〈0.05）.Conclusion：Combined acupuncture and Chinese medicine can remarkably elevate the plasma gastrin and motilin levels in those with reflux esophagitis,regulate the gaslro-esophagus motility,increase the lower esophageal sphincter pressure and thus prevent regurgitation of food.
目的:观察针药并用治疗反流性食管炎的临床疗效。方法:将120例反流性食管炎患者随机分为4组。针药组30例,采用针刺结合中药治疗;中药组30例,口服中药治疗;针刺组30例,采用针刺治疗;西药组30例,口服奥美拉唑肠溶胶囊治疗。四组均治疗60d为1个疗程,治疗前及治疗1个疗程后检测患者血浆胃泌素和胃动素,并进行疗效评价。结果:治疗前各组患者血浆胃泌素和胃动素水平差异无统计学意义,与治疗前比较,治疗后各组患者血浆胃泌素和胃动素水平明显升高(P<0.01);针药组血浆胃泌素和胃动素水平明显高于西药组和中药组(P<0.05)。结论:针药并用可显著提高反流性食管炎患者血浆胃泌素和胃动素水平,调节胃-食管运动,增加下食管括约肌压力,防止食物反流。
