摘要
用耐缺氧实验、全脑缺血实验、小鼠水迷宫实验和小鼠脑组织的MDA含量及SOD活性的测定 ,观察了自制犬胎脑注射液对脑功能的影响。结果表明 ,犬胎脑注射液能显著地对抗氰化钾所引起的组织缺氧 (P <0 0 1) ,明显延长断头后小鼠呼吸维持时间 (P <0 0 0 1) ,明显改善酒精引起小鼠记忆再现障碍 (P <0 0 0 5 ) ,明显降低小鼠脑组织MDA含量 (P <0 0 0 1)和提高SOD活性 (P <0 0 0 1)。
The influence of fetal dog brain injection prepared by the authors on brain function was studied by hypoxia tolerance, cerebral ischemia and swimming maze tests in mice and detecting for the malondialdehyde(MDA) content and superoxide dismutase(SOD) activity in murine brain tissue. The result showed that the injection could significantly improve the tolerance of mice to hypoxia induced by potassium cyanide (p<0.01) , prolong the respiration duration of them after decapitation (p<0.001) and reduce the dysmnesia induced by alcohol (p<0.005). It could also significantly decrease the MDA content in murine brain tissue (p<0.001) and improve the SOD activity in the tissue (p<0.001).
出处
《中国生物制品学杂志》
CAS
CSCD
1999年第3期142-144,共3页
Chinese Journal of Biologicals
