摘要
目的:研究超敏C反应蛋白(hsCRP)和脂蛋白(a)[Lp(a)]对急性心肌梗死行急诊冠状动脉介入治疗(PCI)患者预后的意义。方法:回顾我院自2007-01-2010-04因急性心肌梗死行急诊PCI的118例患者的hsCRP及Lp(a)水平,对hsCRP升高组和正常组以及Lp(a)升高组和正常组在住院期间心血管事件的发生率进行比较。结果:hsCRP升高组心血管事件发生率为52.9%,而hsCRP正常组心血管事件发生率为18.2%,两者比较差异具有统计学意义(P<0.05)。而Lp(a)升高组心血管事件发生率为35.3%,Lp(a)正常组事件发生率为46.4%,两者差异无统计学意义(P>0.05)。结论:hsCRP可作为急性心肌梗死行急诊PCI患者的近期预后的预测因子,而Lp(a)对这类患者的预后无预测作用。
Objective：To study the prognostic significance of high sensitivity C-reactive protein（hsCRP） and lipoprotein（a） in patients received primary percutaneous coronary intervention（PCI） after acute myocardial infarction.Method：We reviewed 118 patients received primary PCI after acute myocardial infarction from January 2007 to April 2010 and their plasma hsCRP and Lp（a） concentration.The cardiovascular event incidence is compared between the hsCRP-elevated group and the hsCRP-normal group,so did between the Lp（a）-elevated group and the Lp（a）-nomal group.Result：It showed that the cardiovascular event incidence in the hsCRP-elevated group was 52.9%,and that in the hsCRP-normal group was 18.2%.There is a significant difference between these two groups（P=0.011）.However,there is no significant difference in the cardiovascular event incidence between the Lp（a） elevated group（35.3%） and the the Lp（a） nomal group（46.4%）,P=0.733.Conclusion：HsCRP,but not Lp（a）,could be a prognostic instruction factor in patients received primary PCI after acute myocardial infarction.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
2011年第2期123-125,共3页
Journal of Clinical Cardiology
