摘要
目的探讨单孔腹腔镜下根治性前列腺切除术（LESS-LRP）治疗早期前列腺癌的临床安全性及可行性。方法经腹膜外途径，应用单孔4通道技术，行LESS-LRP治疗早期前列腺癌2例。应用标准腹腔镜器械和5mm头部可弯腹腔镜。记录患者手术前后PSA、手术时间、估计术中出血量、术中并发症、留置引流管时间、术后疼痛指数（VAPS）、术后住院时间、病理检查等资料，结合文献复习总结手术特点。结果2例LESS-LRP手术均顺利完成，无中转标准腹腔镜或开放手术。2例手术时间分别为280、285min，估计术中出血量分别为400、200ml。术中无严重并发症。术后留置引流时间分别为2、6d，术后第1天VAPS分别为1、0分，术后住院时间分别为14、7d。无继发性出血和切口感染。标本外科切缘均阴性，2例病理分期均为pT2cN0M0。患者术后1个月1例PSA为0．033ng／ml，1例尚未复查。结论LESS-LRP治疗早期前列腺癌值得进一步临床探索性应用。
Objective To verify the safety and feasibility of applying laparoendoscopic singlesite radical prostatectomy （LESS-LRP） in the treatment of prostate cancer. Methods From Sept. to Dec. 2010, LESS LRP was used to treat 2 early stage prostate cancer patients. The LESSLRP was preformed through extra-peritoneal approach by using standard laparoscopic instruments and a 5 mm flexible laparoscope. This technique were evaluated in respects of operative time, estimated blood loss, intraoperative complications, drainage time, post-operative pain score （VAPS）, post-operative hospital stay, pathological results and post-operative PSA levels. Results All procedures of the 2 cases were completed with LESS-LRP without conversion to standard laparoscopic or open radical prostateetomy. The operative times for LESS^LRP were 280 and 285 rain, estimated blood loss were 400 and 200 ml, respectively. There was no severe intraoperative complication. The drainage times were 2 and 6 d, the VAPS in the first post-operative day were I and 0, and post-operative hospital stay were 14 and 7 d. There was no secondary bleeding or wound infection. The 2 prostate cancer ca- ses were all in pathological stage pT2o No M0. Surgical margins of the specimens were negative. The first case showed PSA of 0. 033 ng/ml 1 month after the surgery. Conclusion LESS-LRP can be an exploratory option in clinical for the treatment of prostate cancer.
出处
《中华泌尿外科杂志》
CAS
CSCD
北大核心
2011年第3期209-211,共3页
Chinese Journal of Urology
关键词
单孔腹腔镜手术
前列腺肿瘤
癌
根治性前列腺切除术
Laparoendoscopic single site surgery
Prostatic neoplasmas
Carcinoma
Radical prostatectomy
