期刊文献+

cAMP反应元件结合蛋白(CREB)与细胞凋亡 被引量:5

Cyclic-AMP response binding protein and apoptosis
下载PDF
导出
摘要 cAMP反应元件结合蛋白(CREB)是真核细胞内核转录调节因子,受多因素的激活而调控靶基因,调节细胞凋亡。细胞凋亡与机体生长发育、内环境稳定、防御反应等功能相关。 cAMP response element binding protein,which controls expression of target genes under the activation by various factors and plays an important role in the process of adjusting apoptosis,is the transcription factor located in the nucleus of eukaryotic cells.Apoptosis implicates in the growth,homeostasis,defensive reaction,and so on.
作者 熊果 马康华
出处 《基础医学与临床》 CSCD 北大核心 2011年第3期328-330,共3页 Basic and Clinical Medicine
关键词 CAMP反应元件结合蛋白 细胞凋亡 cAMP response element binding protein apoptosis
  • 相关文献

参考文献5

二级参考文献48

共引文献42

同被引文献36

  • 1向菲,辛建保,汪世瀚,马万里,王峰,白明.己酮可可碱对肺纤维化大鼠MMP-2和TIMP-1表达的影响[J].中国组织化学与细胞化学杂志,2004,13(4):440-444. 被引量:5
  • 2Zhao ZQ. Postconditioning in reperfusion injury: a status report[J].Cardiovasc Drugs Ther, 2010, 24(3): 265-279.
  • 3Tamareille S, Ghaboura N, Treguer F, et al. Myocardial reperfusion injury management: erythropoietin compared with postconditioning[J].Am J Physiol Heart Circ Physiol, 2009, 297(6): H2035-H2043.
  • 4Conti E, Musumeci MB, De Giusti M, et at. IGF1 and athero thrombosis: relevance to pathophysiology and therapy[J].Clin Sci (Lond), 2011, 120(9): 377-402.
  • 5Boucher M, Pesant S, Lei YH, et al. Simultaneous administration of insulin-like growth factor-1 and darbepoetin alfa protects the rat myo cardium against myocardial infarction and enhances angiogenesis[J]. Clin Transl Sci, 2008, 1(1):13-20.
  • 6Jayasankar V, Woo YJ, Pirolli TJ, et al. Induction of anglogenesis and inhibition of apoptosis by hepatocyte growth factor effectively treats postischemic heart failure[J]. Card Surg, 2005, 20(1): 93-101.
  • 7Sinagra G, Bussani R, Abbate A, et al. Left ventricular diastolic filling pattern at Doppler echocardiography and apoptotic rate in fatal acute myocardial infarction[J].Am J Cardiol, 2007, 99 (3) : 307 -309.
  • 8Sun CK, Chang LT, Sheu JJ, et al. Losartan preserves integrity of cardiac gap junctions and PGC-1 alpha gene expression and prevents cellular apoptosis in remote areaof left ventricular myocardium following acute myocardial infarction[J]. Int Heart J, 2007, 48(4): 533-546.
  • 9Mehrhof FB, Muller FU, Bergmann MW, et al. In cardiomyocyte hypoxia, insulin-like growth factor-I-induced antiapoptotic signaling requires phosphatidylinositol-3-OH-kinase-dependent and mitogen-activated protein kinase-dependent activation of the transcription factor cAMP response element-binding protein[J].Circulation, 2001, 104 (17) : 2088-2094.
  • 10Nagy N, Shiroto K, Malik G, et al. Ischemic preconditioning in volves dual eardio-protective axes with p38MAPK as upstream target [J]. J Mol Cell Cardiol, 2007, 42(5): 981-990.

引证文献5

二级引证文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部