摘要
与抑郁障碍相比,双相障碍的临床表现和病程更复杂,治疗更困难,预后更差,自杀风险更大。据报道,双相谱系障碍的患病率为6%,但是在世界范围内尤其是在中国,对这类疾病的识别率和治疗率很低。临床医生需要更熟悉"软双相"的症状,更准确地鉴别双相抑郁与单相抑郁,更准确地区分出共病双相障碍的其他精神障碍,并为预防双相障碍的复发提供更有效的维持治疗。对双相谱系障碍的临床研究需要有效地整合心理治疗和生物治疗。
Compared to patients with depressive disorders,those with bipolar disorders have a more complex clinical presentation and course,a greater risk for treatment non-response,a poorer prognosis and an increased risk of suicide.The reported prevalence of the full spectrum of bipolar disorders is 6% but the rates of recognition and treatment around the world are very low,particularly in China.Clinicians need to become more familiar with the ＂soft＂signs of bipolar spectrum disorders including hypomania,and they need to be better at discriminating bipolar depression from unipolar depression,at identifying patients with other primary disorders who have comorbid bipolar disorders,and at providing the maintenance treatment needed to prevent relapse in patients with bipolar disorders.Clinical research about bipolar spectrum disorders needs to effectively integrate psychological and biological approaches.
出处
《上海精神医学》
2011年第1期12-16,共5页
Shanghai Archives of Psychiatry
关键词
双相障碍
双相抑郁
临床现象学
共病
Bipolar Disorder
Bipolar Depression
Clinical Phenomenology
Comorbidity
