摘要
目的:观察复发性翼状胬肉根治性切除联合自体角膜缘干细胞移植术中应用丝裂霉素C(MMC)的临床疗效。方法:对98例98眼复发性翼状胬肉行根治性切除,将术眼上方或下方带有角膜缘干细胞的结膜瓣移植于胬肉处的巩膜上,术中联合用0.2g/LMMC治疗。结果:术后反应轻,移植片存活,复发率2%。结论:根治性切除联合角膜缘干细胞移植术中应用MMC治疗复发性翼状胬肉,方法简单,胬肉组织切除彻底,重建了角膜缘的结构和功能,恢复了角膜缘的屏障,复发率低,安全有效,值得推广。
AIM： To observe the clinical effects of mitomycin C （MMC） on recurrent pterygium excision combined with corneal limbal stem cell transplantation. METHODS： The radical excision of recurrent pterygium was performed in 98 cases 98 eyes. The conjunctival flap with corneal limbal stem cell was transplanted into sclera and 0.2g/L MMC was used during operation. RESULTS： There was slight response after operation and the recurrence rate was 2% . CONCLUSION： The MMC applied in pterygium excision combined with corneal limbal stem cell transplantation is safe and effective. This method can rebuild the structure and function of corneal limbal, it has low recurrent rate and is worthy to be popularized.
出处
《国际眼科杂志》
CAS
2011年第3期537-538,共2页
International Eye Science
关键词
复发性翼状胬肉
根治性切除
角膜缘干细胞
移植
丝裂霉素
recurrent pterygium
radical excision
corneal limbal stem cell
transplantation
mitomycin
