摘要
目的探讨CT灌注参数血流量(BF)、表面通透性(PS)临界值对鼻咽癌(nasopharyngeal carcinoma,NPC)放疗后局部复发诊断的准确性。资料与方法回顾性分析150例NPC患者放疗后经CT灌注扫描资料,利用受试者工作特征(ROC)曲线分析BF、PS值对诊断NPC放疗后局部复发最佳临界值,计算BF、PS值临界值对诊断局部复发的预测值以及似然比(LR)。结果 CT灌注参数BF、PS临界值诊断NPC放疗后局部复发阳性预测值、阴性预测值分别为90.9%、89.2%和76.4%、70.1%;BF、PS临界值的阳性结果的LR分别为4.7和5,BF、PS阴性结果的LR分别为0.14和0.02。结论 CT灌注成像参数BF、PS临界值对诊断NPC放疗后局部复发具有较好预测值,并具有较好的LR,有助于NPC放疗后局部复发诊断。
Objective To explore the diagnostic accuracy of cutoff value of CT perfusion parameters（BF and PS） in detecting recurrent nasopharyngeal carcinoma （NPC） with radiation therapy.Materials and Methods CT perfusion data of 150 NPC patients with radiation therapy were retrospectively analyzed,Cutoff value in blood flow （BF） and permeability surface（PS）were achieved for diagnosis of recurrent NPC with receiver operator characteristic curves.Predictive value（PV）and likelihood ratio（LR）of BF,PS cut off value were calculated.Results Postive PV,negative PV of BF,PS cut off value for diagnosing recurrent NPC were 90.9%,89.2.0% and 76.4%,70.1% respectively;Positive LR,negative LR of BF,PS cut off value for diagnosing recurrent NPC were LR=4.7,LR=5 and LR=0.14,LR=0.02 respectively.Conclusion The diagnosis of recurrent NPC by cutoff value of CT perfusion parameters has relative high PV and LR,it will help to diagnose local recurrent NPC with radiation therapy.
出处
《临床放射学杂志》
CSCD
北大核心
2011年第2期175-178,共4页
Journal of Clinical Radiology
关键词
复发性鼻咽癌
体层摄影术
X线计算机
似然比
Recurrent nasopharyngeal carcinoma Tomograph
X-ray computed Likelihood ratio
