摘要
生殖支原体是性传播疾病的病原体之一,与非淋菌性尿道炎及女性宫颈炎等疾病密切相关.诊断生殖支原体感染的方法主要有培养、分子生物学及血清学法.目前治疗生殖支原体感染主要是阿奇霉素,但已经出现耐阿奇霉素的生殖支原体临床菌株的报道.针对生殖支原体的治疗药物的药效学研究平台主要有药物敏感性体外实验和动物模型.
Mycoplasma genitalium （Mg）, a pathogen of sexually transmitted disease, is closely related with nongonococcal urethritis and cervicitis. The diagnosis of Mg infection mainly depends on culture,molecular biological and serological methods. Mg infection is primarily treated with azithromycin, but there have been reports on the resistance of Mg to azithromycin. Pharmacodynamic research on antibiotics against Mg is mainly through in vitro drug susceptibility testing and animal model experiment.
出处
《国际皮肤性病学杂志》
2011年第2期106-108,共3页
International Journal of Dermatology and Venereology
基金
基金项目：国家科技重大专项（2009ZX09303-005）
关键词
生殖支原体
抗药性
动物模型
Mycoplasma genitalium Drug resistance Models, animal
