摘要
目的研究林蛙油缓解小鼠体力疲劳作用的影响,探讨林蛙油缓解体力疲劳作用的机制。方法将64只昆明种雄性小鼠随机分为4组:对照组和林蛙油低、中、高剂量组,分别为成人剂量(6g/60kg体重)的1倍、5倍和10倍,每组16只小鼠。对照组灌胃生理盐水;林蛙油各剂量组灌不同剂量的林蛙油匀浆液,连续28d,于末次灌胃1h后,每组8只小鼠进行负重游泳实验;另8只小鼠游泳30min,休息30min后,测定血糖、血尿素氮、血乳酸、肝糖原和肌糖原。结果林蛙油低、中、高剂量组小鼠负重游泳时间均高于对照组(P<0.05,P<0.01);林蛙油低、中、高剂量组小鼠血尿素氮、血乳酸含量降低并低于对照组(P<0.05,P<0.01);血糖、肝糖原和腓肠肌糖原含量增加并高于对照组(P<0.05,P<0.01)。结论林蛙油对小鼠具有一定的缓解疲劳作用。
Objective To study the effects of oviductus rana on the alleviation of physical fatigue in rats and their mechanisms.Methods 64 Kunming male rats were divided into 4 groups by random： the control group and 3 oviductus rana groups,16 mice in each group.Oviductus rana homogenates at 1,5 and 10 times of dosage used for the adults（6g/60kg BW） were given by gavage for the low,medium and high dose oviductus rana groups for 21 days.The rats in the control group were given normal saline by gavage.A loaded swimming test was carried on 8 rats of each group at one hour after the last gavage.The other 8 rats in each group were swimming for 30 minutes and blood,liver and muscle samples were taken after resting for 30 minutes.Blood sugar,blood urea nitrogen and blood lactic acid,hepatic glycogen and muscle glycogen were examined.Results The swimming time insisted in the loaded swimming test in oviductus rana groups was higher than that in the control group（P 0.05,P 0.01）;the content of blood urea nitrogen and lactic acid in the oviductus rana groups was dropped and lower than the control group（P 0.05,P 0.01）;the content of blood sugar,hepatic glycogen and muscle glycogen was raised and higher than the control group（P 0.05,P 0.01）.Conclusion There is an effect of Oviducts Rana on alleviating physical fatigue in mice.
出处
《卫生研究》
CAS
CSCD
北大核心
2011年第2期231-232,共2页
Journal of Hygiene Research
基金
吉林省教育厅“十二五”科学技术研究重点课题
关键词
林蛙油
缓解疲劳
oviductus rana
alleviating fatigue
